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Phytosphingosine

Phytosphingosine

 

  • Phytosphingosine(PS) is a natural sphingolipid in human skin  that maintain skin barrier function , as well as,  anti-microbial and anti-inflammatory properties

 

 

 

Phytosphingosine properties

 

Interleukin 1 alpha (IL-1α): Marker of inflammation

Peptide expressed by many cells including epidermal keratinocytes

  • Key role in regulation of acute inflammation with a prime position in the cytokine cascade
    • Switches on production of additional cytokines, prostaglandins.
  • Important mediator for the induction of a variety of skin disorders :
    • Allergic & irritant dermatoses
    • Photoallergic & phototoxic skin reactions including sunburn
    • Degradation of collagen matrix via expression of matrix metalloproteases (MMP‘s)

 

The Anti-Inflammatory and Anti-Microbial Properties of Phytosphingosine work synergistically.

 

Phytosphingosine on acne patients

 

 

Abbreviations used:

• PS = Phytosphingosine

• BPO = Benzoyl Peroxide

 

 

                        Phytosphingosine

  • is naturally present in the skin
  • shows excellent clinical results on Acne
  • has two anti-acne properties, which work synergistically:
  • anti-inflammatory activity
  • anti-microbial activity
  • Anti-Cellulite
  • Cellulite caused by inflammation of the conjunctive tissueà leading to swelling
  • Phytosphingosine à Anti-Cellulite

    -  reduction of swelling

    -  promotion of blood circulation

  • Prevent & reduce skin darkness, puffiness, dark eye circle
  • Prevention of puff formationà prevent swelling in the fat puffiness
  • Promotion of blood circulation
  • Strengthening of the microcapillaries/ disappearance of black circlesà reduce skin darkness, dark eye circle
  • Repairs and protects even the fragile eye area and successfully treat the appearance of lines, dryness, puffiness and dark circles