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Collagen Support
The Rejuran Program is a personalized skin rejuvenation plan that features polynucleotides (PN) — naturally derived DNA fragments from wild salmon. These biocompatible molecules are gently introduced into the skin during the program to help improve hydration, texture, and overall revitalization.
Supports Skin Recovery
The Rejuran Program is a skin rejuvenation treatment that utilizes polynucleotide (PN) technology designed to support skin revitalization and help improve the appearance of concerns such as wrinkles, scars, large pores, redness, and pigmentation.
Helps Maintain Skin Elasticity and Fine Lines
Through the Rejuran Program’s polynucleotide-based formulation, this treatment supports the skin’s extracellular matrix (ECM) and hydration, which may contribute to improved skin elasticity and a reduced appearance of fine lines over time.
Supports an Even Skin Tone and Smoother Texture
The Rejuran Program works in harmony with the skin’s natural renewal process. By introducing naturally derived polynucleotides, it helps balance skin tone and supports smoother texture, contributing to a naturally refreshed appearance.
Recognized for Biocompatibility
The Rejuran Program contains biocompatible polynucleotides (PN) that have been widely used in aesthetic dermatology to support skin repair and rejuvenation. Individual responses may vary depending on each person’s skin condition.
Hydration and Skin Elasticity Support
Powered by Rejuran Program’s polynucleotide complex, the program helps maintain skin hydration and elasticity, contributing to a more supple and refreshed look with consistent care.
DNA fragments extracted from wild salmon, refined through the company’s patented DNA Optimizing Technology (DOT™).
Clear, colorless viscous solution.
Slowly degrades while maintaining uniform structure in tissue.
Designed to be compatible with human skin, with minimal reported side effects.
Supports the skin’s natural reparative process.
Helps maintain skin elasticity and supports the biological condition of the dermis and epidermis.
The Rejuran Program is designed to support skin revitalization by helping maintain the skin’s natural regenerative process.
Remarks:
A Comprehensive Overview of Rejuran Program’s Formulations
*Individual results may vary depending on individual patient
Pharmaresearch Products. Rejuran: Polynucleotide (PN) Skin Rejuvenation & Regeneration. 2020. Available from: Medical JJ.
Contains biocompatible polynucleotides (PN) extracted from wild salmon, which support the skin’s natural renewal process.
A natural component that supports skin hydration.
Contains lidocaine, commonly used to support comfort during treatment.
*Individual results may vary depending on individual patient
Rejuran HB Program gives both the skin healing strengths of PN and the deep skin hydrating benefits of HA
Rejuran HB Program contains lidocaine to enhance treatment comfort and optimize the injection experience
Pharmaresearch Products. Rejuran: Polynucleotide (PN) Skin Rejuvenation & Regeneration. 2020. Available from: Medical JJ.
The Rejuran Program is a skin rejuvenation plan designed to support the skin’s natural repair process at the cellular level, helping the skin appear smoother, firmer, and naturally refreshed over time.
*Individual results may vary depending on individual patient
*Individual results may vary depending on individual patient
Pharmaresearch Products. Rejuran: Polynucleotide (PN) Skin Rejuvenation & Regeneration. 2020. Available from: Medical JJ.
*Individual results may vary depending on individual patient
Pharmaresearch Products. Rejuran: Polynucleotide (PN) Skin Rejuvenation & Regeneration. 2020. Available from: Medical JJ.
Program Rejuran is designed to support fibroblast activity, which may contribute to collagen production. Studies have examined its effects on skin rejuvenation.
*Individual results may vary depending on individual patient
Chang sik Pak et al., A phase 3, randomized, double-blind, matched-pairs, active-controlled clinical trial and preclinical animal study to compare
the durability, efficacy and safety between polynucleotide filler and hyaluronic acid filler in the correction of crow’s feet; JKMS 2014;201-209.
Rejuran Program supports skin elasticity with regenerating epidermis and dermis healthier from thinned and damaged skin.
*Individual results may vary depending on individual patient
Chang sik Pak et al., A phase 3, randomized, double-blind, matched-pairs, active-controlled clinical trial and preclinical animal study to compare
the durability, efficacy and safety between polynucleotide filler and hyaluronic acid filler in the correction of crow’s feet; JKMS 2014;201-209.
The Rejuran Program supports epidermal and dermal layers, contributing to skin structure. This may help reinforce the skin barrier against external factors associated with premature skin aging
*Individual results may vary depending on individual patient
Seoul national university bundang hospital report.
The Rejuran Program supports skin hydration and elasticity, with observed improvements of 14.69% in hydration and 21.78% in elasticity in a clinical study. Individual results may vary.
*Individual results may vary depending on individual patient
Long chain polynucleotides gel and skin biovitalization. Journal of Plastic Dermatology 2007; 3, 3
A total of 4 Rejuran Program sessions are typically scheduled at two-week intervals.
The pore and skin thickness were markedly improved in 30s, whereas skin tone, melanin, wrinkles, and sagging were noticeably improved in 40s
*Individual results may vary depending on individual patient
Park, K. Y., Seok, J., Rho, N. K., Kim, B. J., & Kim, M. N. (2015). Long-chain polynucleotide filler for skin rejuvenation:
efficacy and complications in five patients. Dermatologic Therapy, 29(1), 37–40.
*Individual results may vary depending on individual patient
Rejuran I Program were performed every two weeks for a total of three times over 12 weeks.
Polynucleotide (PN) administration has been studied for its role in improving the appearance of crow’s feet and fine wrinkles around eyes. and also improves elasticity around eyes area. It has also been evaluated for its potential to support skin elasticity in the under-eye area.
Before and 6 Months After The Treatment
*Individual results may vary depending on individual patient
Before and 6 Months After The Treatment
*Individual results may vary depending on individual patient
A Phase III, Randomized, Double-Blind, Matched-Pairs, Active-Controlled Clinical Trial to Compare the Durability, Efficacy and Safety between
Polynucleotide Filler and Hyaluronic Acid Filler in the Correction of Crow’s Feet, In house report, 2014
The experimental group and control group were randomly assigned to compare the efficacy for 16 weeks.
– Experimental group: fractional laser + Program Rejuran s
– Control group: fractional laser + saline
The Vancouver Scar Scale (VSS), global photographic assessment, and objective scar were assessed using 3D camera at baseline and after surgery.
Adjuvant administration of PN, in combination with conventional fractional laser treatment, has been studied for its potential role in supporting wound healing and improving the appearance of post-operative scars after thyroidectomy. Individual responses may vary.
*Individual results may vary depending on individual patient
Preventive Effect of Polynucleotide on Post-thyroidectomy Scars: A Randomized, Double-Blinded, Controlled Trial Lasers in Surgery and
Medicine (SCI), 2018, 755-762
*Individual results may vary depending on individual patient
Preventive Effect of Polynucleotide on Post-thyroidectomy Scars: A Randomized, Double-Blinded, Controlled Trial Lasers in Surgery and
Medicine (SCI), 2018, 755-762
Rejuran Program is a skin treatment approach, providing a different approach from filler program or laser treatments. It works by supporting the skin’s natural regenerative process, which may help maintain collagen structure and skin elasticity.
This approach supports skin maintenance with a course of four treatments, typically scheduled 2-3 weeks apart, followed by sessions every six months to help maintain skin health.
While some individuals may experience slight swelling or papules on the treated areas immediately after the procedure, these effects are usually temporary and may subside within 24 hours. Most individuals can resume their daily activities as usual, but responses may vary.
For comprehensive skin care, Rejuran program is applied to the entire face rather than just the eye area, supporting overall skin appearance and addressing visible signs associated with aging and environmental factors. Treatment suitability varies for each individual.
Rejuran Program contains bio-compatible DNA fragments and is designed to support skin revitalization. It is considered for areas that may not be commonly treated with a hyaluronic acid filler program or toxin.
Not when receiving treatment with Rejuran Program. The main ingredient, PN, is considered to have a dose-dependent effect, allowing the skin to gradually absorb and benefit from the treatment.
Rejuran Program is a skin treatment approach, providing a different approach from filler program or laser treatments. It works by supporting the skin’s natural regenerative process, which may help maintain collagen structure and skin elasticity.
This approach supports skin maintenance with a course of four treatments, typically scheduled 2-3 weeks apart, followed by sessions every six months to help maintain skin health.
While some individuals may experience slight swelling or papules on the treated areas immediately after the procedure, these effects are usually temporary and may subside within 24 hours. Most individuals can resume their daily activities as usual, but responses may vary.
For comprehensive skin care, Rejuran program is applied to the entire face rather than just the eye area, supporting overall skin appearance and addressing visible signs associated with aging and environmental factors. Treatment suitability varies for each individual.
Rejuran Program contains bio-compatible DNA fragments and is designed to support skin revitalization. It is considered for areas that may not be commonly treated with a hyaluronic acid filler program or toxin.
Not when receiving treatment with Rejuran Program. The main ingredient, PN, is considered to have a dose-dependent effect, allowing the skin to gradually absorb and benefit from the treatment.
– Inject with 27- or 30-gauge needle just beneath the dermis after mixing with the lidocaine.
– Anti-pain medications can be taken before the treatment.
– Forehead, Glabella, Around Eyes: Needle – Midface, Jawline: Cannula
– Around lips: Needle
– This depends on the type of dermal filler program or injectable used.
– Some practitioners may suggest scheduling the REJURAN Program a few weeks before other dermal injectable treatments, depending on individual assessment.
– A medical evaluation is recommended before treatment for individuals who have previously undergone facial injectables.
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